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Ebola

Ebola virus disease is a severe illness that was first discovered in humans in 1976 in South Sudan and the Democratic Republic of Congo, formerly Zaire. Since then, a number of outbreaks have occurred in central and western Africa.

Caused by an infection with an orthoebolavirus, Ebola is highly contagious, but it is transmitted only through direct contact with bodily fluids of an infected person or contaminated objects. The incubation period is 2 to 21 days. Currently, Ebola is not considered a threat outside of certain countries in sub-Saharan Africa.

 

More about Ebola

Fever, severe headache, muscle and joint pain, weakness, fatigue, nausea, vomiting, diarrhea, abdominal pain and unexplained bleeding are symptoms of Ebola. Without prompt and appropriate treatment, as many as 80% to 90% of people who become sick with Ebola virus disease may die.

There are currently two treatments that have been approved by the Food and Drug Administration to treat disease caused by the Orthoebolavirus zairense species of Ebola, one of the four types of orthoebolaviruses that cause Ebola disease in people.

FDA approved an Ebola vaccine in 2019 that has been found to be safe and protective against Orthoebolavirus zairense, the type of the virus that has caused the largest and most deadly Ebola outbreaks to date. This vaccine is recommended for U.S. adults who are at potential risk of exposure to the virus.

The risk of getting Ebola virus disease while traveling is very low. Travelers can reduce their risk while traveling in or living in regions where orthoebolaviruses may be present by avoiding contact with blood or bodily fluids from sick people and from animals such as bats or nonhuman primates, and by not handling bushmeat or animals that may be infected.

The U.S. Centers for Disease Control and Prevention has travel notices in place for the Democratic Republic of Congo and Uganda with information for Americans planning travel to either country. Both countries are currently experiencing an Ebola outbreak caused by the Bundibugyo virus.

On May 5, 2026, a cluster of severe illness in the Ituri Province in the northeastern part of the Democratic Republic of Congo was reported to the World Health Organization. The outbreak has been linked to Bundibugyo virus, one of the four types of orthoebolaviruses that cause Ebola disease in people. There are no approved vaccines or treatments for Bundibugyo virus. Death rates in previous outbreaks of Bundibugyo virus have ranged from 30% to 50%.

As of May 19, the outbreak had caused more than 500 suspected cases, including over 130 deaths, in Congo and neighboring Uganda, according to WHO. These numbers are likely to change as the outbreak evolves.

WHO declared the outbreak a public health emergency of international concern on May 17. The outbreak doesn’t meet the criteria of a pandemic emergency like COVID-19, according to WHO, which advised against the closure of international borders. (See IDSA’s statement on the May 18 order from the U.S. Centers for Disease Control and Prevention banning some people from entering the United States from Congo, South Sudan and Uganda.)

To date, no cases of Ebola disease have been confirmed in the United States from the outbreak. The overall risk to the American public remains low, according to CDC. On May 18, CDC confirmed one case of Ebola in an American who was exposed as part of their work in Congo and was being moved to Germany for treatment. Six additional Americans who are high-risk contacts were also being transported to Germany or the Czech Republic for monitoring.

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